J147 is an experimental drug with reported effects against both Alzheimer’s disease and ageing in mouse models of accelerated aging. The approach that lead to development of the J147 drug was to screen candidate molecules for anti-aging effects, instead of targeting the amyloid plaques.
J147 may potentially be successful in treating other neurodegenerative diseases, such as Parkinson’s. “People have always thought that you need separate drugs for Alzheimer’s, Parkinson’s and stroke,” said Schubert. “But it may be that by targeting aging, we can treat or slow down many pathological conditions that are old-age associated.”