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F-Phenibut (also known as 4-Fluorophenibut, Fluorophenibut, Fluorobut and CGP-11130) is a central nervous system depressant and closely related structural analog of phenibut. F-Phenibut possesses an effect profile similar to phenibut but with a faster onset, significantly increased potency, and shorter total duration.
Physical effects:
Stimulation and Sedation – At lower doses, F-Phenibut has a mild physical and mental stimulation effect, encouraging movement, wakefulness, productivity and socialization. At higher doses, however, it becomes physically sedating, encouraging sleep and lethargy. Sleeping after dosing a small amount may result in a deep, restful sleep which can leave the user feeling refreshed and alert upon waking.
Physical euphoria
Respiratory depression
Nausea – F-Phenibut can induce mild to extreme nausea depending greatly on dose and tolerance. It usually manifests roughly 90 minutes after the initial dose and generally involves waves of nausea accompanied by excessive sweating and vomiting.
Motor control loss
Stomach cramps
Dizziness
Increased perspiration
Dehydration – Dehydration is typically reported to occur from regular multiday usage or excessive doses; however, it can also be present even in average doses of the substance (although perhaps to a lesser degree than phenibut).
Temperature regulation loss
Headaches – Moderate to high doses have been reported to be a induce a mild to strong headache, typically many hours after dosing or during the comedown period.
Muscle cramps – Muscle cramps and joint pain are sometimes accompanied at high doses.
Frequent urination
Appetite enhancement
Cognitive effects:
Empathy, love, and sociability enhancement – Unlike alcohol which merely increases sociability through disinhibition, F-Phenibut presents entactogenic effects which, although much weaker than that of traditional entactogens such as MDMA, are still prominent and well-defined even at moderate doses.
Compulsive redosing – This component is highly pronounced in comparison to phenibut.
Disinhibition
analysis suppression – High doses will usually induce a state of mild stupor and confusion.
Thought deceleration
Cognitive euphoria
Motivation enhancement
Anxiety suppression
Depression – A low mood can be experienced as an after effect of high or frequent dosing.
Amnesia – In comparison to many other GABAergics, this component is very weak except at very high doses.